Tucked away across a small bridge in the warren of central Castello, this enchanting hotel occupies a 16th-century palazzo, though it’s been a hotel since 1911. Rooms sport an old-fashioned Venetian style, with Florentine furniture, hand-painted beds, and colorful textiles (antiques and paintings are scattered throughout), but are updated with air-conditioning and satellite TV. Some rooms have a view over a canal, others over the shady courtyard and the city. Don’t miss the top floor, where the panoramic terrace is a pleasant spot for an aperitif. They’ll also take you to Murano for free, but you have to find your own way back.